Vesiclepedia 2024: an extracellular vesicles and extracellular particles repository

Chitti, Sai Vara Prasad; Gummadi, Sriram; Kang, Taeyoung; Shahi, Sanjay; Marzan, Akbar Lulu; Nedeva, Christina; Sanwlani, Rahul; Bramich, Kyle; Stewart, Sarah; Petrovska, Monika; Sen, Biswadeep; Ozkan, Alper; Akinfenwa, Maria; Fonseka, Pamali; Mathivanan, Suresh

doi:10.26181/25321984.v1

1416826_Chitti,S_2024.pdf (1.74 MB)

Vesiclepedia 2024: an extracellular vesicles and extracellular particles repository

journal contribution

posted on 2024-03-01, 03:53 authored by Sai Vara Prasad ChittiSai Vara Prasad Chitti, Sriram GummadiSriram Gummadi, Taeyoung KangTaeyoung Kang, Sanjay ShahiSanjay Shahi, Akbar Lulu MarzanAkbar Lulu Marzan, Christina Nedeva, Rahul SanwlaniRahul Sanwlani, Kyle BramichKyle Bramich, Sarah StewartSarah Stewart, Monika PetrovskaMonika Petrovska, Biswadeep SenBiswadeep Sen, Alper Ozkan, Maria Akinfenwa, Pamali FonsekaPamali Fonseka, Suresh MathivananSuresh Mathivanan

Vesiclepedia (http://www.microvesicles.org) is a free web-based compendium of DNA, RNA, proteins, lipids and metabolites that are detected or associated with extracellular vesicles (EVs) and extracellular particles (EPs). EVs are membranous vesicles that are secreted ubiquitously by cells from all domains of life from archaea to eukaryotes. In addition to EVs, it was reported recently that EPs like exomeres and supermeres are secreted by some mammalian cells. Both EVs and EPs contain proteins, nucleic acids, lipids and metabolites and has been proposed to be implicated in several key biological functions. Vesiclepedia catalogues proteins, DNA, RNA, lipids and metabolites from both published and unpublished studies. Currently, Vesiclepedia contains data obtained from 3533 EV studies, 50 550 RNA entries, 566 911 protein entries, 3839 lipid entries, 192 metabolite and 167 DNA entries. Quantitative data for 62 822 entries from 47 EV studies is available in Vesiclepedia. The datasets available in Vesiclepedia can be downloaded as tab-delimited files or accessible through the FunRich-based Vesiclepedia plugin.

Funding

S.M. is supported by Australian Research Council FT (FT180100333). P.F is supported by NHMRC EL1 fellowship (2017138).

History

Publication Date

2024-01-05

Journal

Nucleic Acids Research

Volume

52

Issue

D1

Pagination

5p. (p. D1694-D1698)

Publisher

Oxford University Press

ISSN

0305-1048

Rights Statement

© The Author(s) 2023. Published by Oxford University Press on behalf of Nucleic Acids Research. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.