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Use of multidimensional item response theory methods for dementia prevalence prediction: an example using the Health and Retirement Survey and the Aging, Demographics, and Memory Study

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posted on 14.09.2021, 02:51 by E Nichols, F Abd-Allah, A Abdoli, A Abualhasan, E Abu-Gharbieh, A Afshin, RO Akinyemi, FM Alanezi, V Alipour, A Almasi-Hashiani, J Arabloo, A Ashraf-Ganjouei, G Ayano, JL Ayuso-Mateos, AA Baig, M Banach, MA Barboza, SL Barker-Collo, BT Baune, AS Bhagavathula, K Bhattacharyya, A Bijani, A Biswas, A Boloor, C Brayne, H Brenner, K Burkart, S Burugina Nagaraja, F Carvalho, LFS Castro-de-Araujo, F Catalá-López, E Cerin, N Cherbuin, DT Chu, X Dai, AR de Sá-Junior, S Djalalinia, A Douiri, David EdvardssonDavid Edvardsson, SI El-Jaafary, S Eskandarieh, A Faro, F Farzadfar, VL Feigin, SM Fereshtehnejad, E Fernandes, P Ferrara, I Filip, F Fischer, S Gaidhane, L Galluzzo, GG Gebremeskel, A Ghashghaee, A Gialluisi, EV Gnedovskaya, M Golechha, R Gupta, V Hachinski, MR Haider, TG Haile, M Hamiduzzaman, GJ Hankey, SI Hay, G Heidari, R Heidari-Soureshjani, HC Ho, M Househ, BF Hwang, L Iacoviello, OS Ilesanmi, IM Ilic, MD Ilic, SSN Irvani, M Iwagami, IO Iyamu, RP Jha, R Kalani, A Karch, AS Kasa, YS Khader, EA Khan, MN Khatib, YJ Kim, S Kisa, A Kisa, M Kivimäki, A Koyanagi, I Landires, S Lasrado, B Li, SS Lim, X Liu, S Madhava Kunjathur, A Majeed, P Malik, MM Mehndiratta, RG Menezes, Y Mohammad, S Mohammed
Note: Not all authors listed; please see article (last page) for full list of Contributors).
Background: Data sparsity is a major limitation to estimating national and global dementia burden. Surveys with full diagnostic evaluations of dementia prevalence are prohibitively resource-intensive in many settings. However, validation samples from nationally representative surveys allow for the development of algorithms for the prediction of dementia prevalence nationally. Methods: Using cognitive testing data and data on functional limitations from Wave A (2001–2003) of the ADAMS study (n = 744) and the 2000 wave of the HRS study (n = 6358) we estimated a two-dimensional item response theory model to calculate cognition and function scores for all individuals over 70. Based on diagnostic information from the formal clinical adjudication in ADAMS, we fit a logistic regression model for the classification of dementia status using cognition and function scores and applied this algorithm to the full HRS sample to calculate dementia prevalence by age and sex. Results: Our algorithm had a cross-validated predictive accuracy of 88% (86–90), and an area under the curve of 0.97 (0.97–0.98) in ADAMS. Prevalence was higher in females than males and increased over age, with a prevalence of 4% (3–4) in individuals 70–79, 11% (9–12) in individuals 80–89 years old, and 28% (22–35) in those 90 and older. Conclusions: Our model had similar or better accuracy as compared to previously reviewed algorithms for the prediction of dementia prevalence in HRS, while utilizing more flexible methods. These methods could be more easily generalized and utilized to estimate dementia prevalence in other national surveys.

History

Publication Date

11/08/2021

Journal

BMC Medical Informatics and Decision Making

Volume

21

Article Number

241

Pagination

21p.

Publisher

Springer Nature

ISSN

1472-6947

Rights Statement

The Author reserves all moral rights over the deposited text and must be credited if any re-use occurs. Documents deposited in OPAL are the Open Access versions of outputs published elsewhere. Changes resulting from the publishing process may therefore not be reflected in this document. The final published version may be obtained via the publisher’s DOI. Please note that additional copyright and access restrictions may apply to the published version.

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