La Trobe
1157843_Elliott,S_2021.pdf (534.5 kB)

Use of magnetic resonance imaging-guided radiotherapy for breast cancer: a scoping review protocol

Download (534.5 kB)
journal contribution
posted on 15.03.2021, 06:43 by S Elliott, A Berlangieri, Jason Wasiak, M Chao, F Foroudi
© 2021, The Author(s). Background: In recent years, we have seen the incorporation of magnetic resonance imaging (MRI) simulators into radiotherapy centres and the emergence of the new technology of MR linacs. However, the significant health care resources associated with this advanced technology impact immediate widespread use and availability. There are currently limited studies to demonstrate the clinical effectiveness and inform decision-making on the use of MRI in radiotherapy. The objective of this scoping review is to identify and map the existing evidence surrounding the clinical implementation of MRI-guided radiotherapy in patients with breast cancer. It also aims to identify challenges and knowledge gaps in the literature. Methods: We will perform a comprehensive search in MEDLINE and EMBASE databases from January 2010 onwards. Grey literature sources will include the WHO International Clinical Trials Registry Platform. We will include systematic reviews, randomised and non-randomised controlled studies published in English. Literature should examine the use of magnetic resonance imaging-guided radiotherapy in adults with breast cancer, regardless of cancer stage or severity. Two reviewers will independently screen all titles, abstracts and full-text reports. Data will be extracted and summarised using qualitative (e.g. content and thematic analysis) methods and presented in tables. Discussion: The results from this review will consolidate the evidence surrounding MRI-guided radiotherapy for breast cancer, contributing to the development and optimisation of patient selection, simulation, planning, treatment delivery, quality assurance and research, to help improve patient outcomes, cancer care and treatment for women with breast cancer. Systematic review registration: The protocol is available on Open Science Framework at DOI https://doi.org/10.17605/OSF.IO/8TEV6

History

Publication Date

01/02/2021

Journal

Systematic Reviews

Volume

10

Issue

1

Article Number

44

Pagination

7p.

Publisher

BioMed Central

ISSN

2046-4053

Rights Statement

The Author reserves all moral rights over the deposited text and must be credited if any re-use occurs. Documents deposited in OPAL are the Open Access versions of outputs published elsewhere. Changes resulting from the publishing process may therefore not be reflected in this document. The final published version may be obtained via the publisher’s DOI. Please note that additional copyright and access restrictions may apply to the published version.