239149_Waters,S_2018.pdf (1.16 MB)
The methylome of vertebrate sex chromosomes
journal contribution
posted on 2022-02-11, 05:46 authored by SA Waters, A Capraro, KL McIntyre, Jennifer GravesJennifer Graves, PD WatersDNA methylation is a key epigenetic modification in vertebrate genomes known to be involved in the regulation of gene expression, X chromosome inactivation, genomic imprinting, chromatin structure, and control of transposable elements. DNA methylation is common to all eukaryote genomes, but we still lack a complete understanding of the variation in DNA methylation patterns on sex chromosomes and between the sexes in diverse species. To better understand sex chromosome DNA methylation patterns between different amniote vertebrates, we review literature that has analyzed the genome-wide distribution of DNA methylation in mammals and birds. In each system, we focus on DNA methylation patterns on the autosomes versus the sex chromosomes.
Funding
Supported by an Australian Research Council Discovery Project DP180100931.
History
Publication Date
2018-01-01Journal
GenesVolume
9Issue
5Article Number
230Pagination
13p. (p. 1-13)Publisher
MDPIISSN
2073-4425Rights Statement
© 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). The Author reserves all moral rights over the deposited text and must be credited if any re-use occurs.Publisher DOI
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