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The genome sequence of the Australian filarial nematode, Cercopithifilaria johnstoni

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posted on 08.12.2021, 23:24 authored by Warwick GrantWarwick Grant, SR Doyle, Kirsty McCann
Wellcome Open Research is an Open Research platform. This publication is: version 2; peer review: 3 approved.
We present a genome assembly and annotation of an individual female Cercopithifilaria johnstoni, a parasitic filarial nematode that is transmitted by hard ticks (Ixodidae) to infect a broad range of native Australian murid and marsupial hosts. The genome sequence is 76.9 Mbp in length, and although in draft form (N50 = 99 kbp, N50[n] = 232), is largely complete based on universally conserved orthologs (BUSCOs; genome = 94.9%, protein = 96.5%) and relative to other related filarial species. These data represent the first genomic resources for the genus Cercopithifilaria, a group of parasites with a broad host range, and form the basis for comparative analysis with the human-infective parasite, Onchocerca volvulus, both of which are responsible for similar eye and skin pathologies in their respective hosts.

History

Publication Date

03/12/2021

Journal

Wellcome Open Research

Volume

6

Article Number

259

Pagination

19p.

Publisher

Taylor & Francis

ISSN

2398-502X

Rights Statement

The Author reserves all moral rights over the deposited text and must be credited if any re-use occurs. Documents deposited in OPAL are the Open Access versions of outputs published elsewhere. Changes resulting from the publishing process may therefore not be reflected in this document. The final published version may be obtained via the publisher’s DOI. Please note that additional copyright and access restrictions may apply to the published version.

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