1187381_McCan,K_2021.pdf (3.5 MB)
The genome sequence of the Australian filarial nematode, Cercopithifilaria johnstoni
journal contribution
posted on 2021-12-08, 23:24 authored by Warwick GrantWarwick Grant, SR Doyle, Kirsty McCannWellcome Open Research is an Open Research platform. This publication is: version 2; peer review: 3 approved.
We present a genome assembly and annotation of an individual female Cercopithifilaria johnstoni, a parasitic filarial nematode that is transmitted by hard ticks (Ixodidae) to infect a broad range of native Australian murid and marsupial hosts. The genome sequence is 76.9 Mbp in length, and although in draft form (N50 = 99 kbp, N50[n] = 232), is largely complete based on universally conserved orthologs (BUSCOs; genome = 94.9%, protein = 96.5%) and relative to other related filarial species. These data represent the first genomic resources for the genus Cercopithifilaria, a group of parasites with a broad host range, and form the basis for comparative analysis with the human-infective parasite, Onchocerca volvulus, both of which are responsible for similar eye and skin pathologies in their respective hosts.History
Publication Date
2021-12-03Journal
Wellcome Open ResearchVolume
6Article Number
259Pagination
19p.Publisher
Taylor & FrancisISSN
2398-502XRights Statement
The Author reserves all moral rights over the deposited text and must be credited if any re-use occurs. Documents deposited in OPAL are the Open Access versions of outputs published elsewhere. Changes resulting from the publishing process may therefore not be reflected in this document. The final published version may be obtained via the publisher’s DOI. Please note that additional copyright and access restrictions may apply to the published version.Publisher DOI
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