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Proteomic Insights into Extracellular Vesicle Biology – Defining Exosomes and Shed Microvesicles.pdf (568.25 kB)
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Proteomic insights into extracellular vesicle biology - defining exosomes and shed microvesicles

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journal contribution
posted on 2021-08-13, 01:34 authored by David GreeningDavid Greening, Rong Xu, SK Gopal, A Rai, Richard SimpsonRichard Simpson
This review focuses on the emerging importance of discovery proteomics (high-throughput, unbiased quantitative protein identification) and targeted proteomics (hypothesis-driven quantitative protein subset analysis) mass spectrometry (MS)-based strategies in EV biology, especially exosomes and shed microvesicles.


This work was supported, in part, by the National Health and Medical Research Council (NHMRC) of Australia project grants, grant number 1057741 (R.J. Simpson), La Trobe University Leadership RFA Grant (D.W. Greening and R.J. Simpson), La Trobe Institute for Molecular Science Molecular Biology Stone Fellowship (D.W. Greening), and La Trobe University Start-up Grant (D.W. Greening). R. Xu, S. Gopal, and A. Rai are supported by La Trobe University Post Graduate Scholarships.


Publication Date



Expert Review of Proteomics






27p. (p. 69-95)


Taylor and Francis



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