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Precision nomenclature for the new genomics

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posted on 11.02.2022, 05:35 by HA Lewin, Jennifer GravesJennifer Graves, OA Ryder, AS Graphodatsky, SJ O'Brien
The confluence of two scientific disciplines may lead to nomenclature conflicts that require new terms while respecting historical definitions. This is the situation with the current state of cytology and genomics, which offer examples of distinct nomenclature and vocabularies that require reconciliation. In this article, we propose the new terms C-scaffold (for chromosome-scale assemblies of sequenced DNA fragments, commonly named scaffolds) and scaffotype (the resulting collection of C-scaffolds that represent an organism's genome). This nomenclature avoids conflict with the historical definitions of the terms chromosome (a microscopic body made of DNA and protein) and karyotype (the collection of images of all chromosomes of an organism or species). As large-scale sequencing projects progress, adoption of this nomenclature will assist end users to properly classify genome assemblies, thus facilitating genomic analysis.

History

Publication Date

01/01/2019

Journal

GigaScience

Volume

8

Issue

8

Article Number

giz086

Pagination

3p.

Publisher

Oxford University Press

ISSN

2047-217X

Rights Statement

Copyright © The Author(s) 2019. Published by Oxford University Press. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. The Author reserves all moral rights over the deposited text and must be credited if any re-use occurs.

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