La Trobe

File(s) stored somewhere else

Please note: Linked content is NOT stored on La Trobe and we can't guarantee its availability, quality, security or accept any liability.

Perspectives on single particle imaging with x rays at the advent of high repetition rate x-ray free electron laser sources

journal contribution
posted on 02.12.2020, 02:42 by Johan Bielecki, Filipe RNC Maia, Adrian MancusoAdrian Mancuso
© 2020 Author(s). X-ray free electron lasers (XFELs) now routinely produce millijoule level pulses of x-ray photons with tens of femtoseconds duration. Such x-ray intensities gave rise to the idea that weakly scattering particles - perhaps single biomolecules or viruses - could be investigated free of radiation damage. Here, we examine elements from the past decade of so-called single particle imaging with hard XFELs. We look at the progress made to date and identify some future possible directions for the field. In particular, we summarize the presently achieved resolutions as well as identifying the bottlenecks and enabling technologies to future resolution improvement, which in turn enables application to samples of scientific interest.

History

Publication Date

06/08/2020

Journal

Structural Dynamics

Volume

7

Issue

4

Article Number

040901

Pagination

5p.

Publisher

AIP Publishing

ISSN

2329-7778

Rights Statement

The Author reserves all moral rights over the deposited text and must be credited if any re-use occurs. Documents deposited in OPAL are the Open Access versions of outputs published elsewhere. Changes resulting from the publishing process may therefore not be reflected in this document. The final published version may be obtained via the publisher’s DOI. Please note that additional copyright and access restrictions may apply to the published version.