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Parenthood With Kidney Failure: Answering Questions Patients Ask About Pregnancy

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posted on 2022-10-03, 23:07 authored by S Jesudason, A Williamson, Brooke HuuskesBrooke Huuskes, E Hewawasam
Achieving parenthood can be an important priority for women and men with kidney failure. In recent decades, the paradigm has shifted toward greater support of parenthood, with advances in our understanding of risks related to pregnancy and improvements in obstetrical and perinatal care. This review, codesigned by people with personal experience of kidney disease, provides guidance for nephrologists on how to answer the questions most asked by patients when planning for parenthood. We focus on important issues that arise in preconception counseling for women receiving dialysis and postkidney transplant. We summarize recent studies reflecting pregnancy outcomes in the modern era of nephrology, obstetrical, and perinatal care in developed countries. We present visual aids to help clinicians and women navigate pregnancy planning and risk assessment. Key principles of pregnancy management are outlined. Finally, we explore outcomes of fatherhood in males with kidney failure.


The authors are very grateful for insightful input from members of our Parenthood in Kidney Disease Consumer Advisory Group (Jane Boag, Dr. Shyam Muthur-amalingam, Laura Heffernan, Adela Tolic, Kelli Owen, Dr Charmaine Green, Carolina Maistry) , particularly for the framework of questions patients may ask and design of figures for patient counseling. EH is supported by the Better Evidence and Translation in Chronic Kidney Disease (BEAT-CKD) Program Grant (National Health and Medical Research Council, Australia, APP1092957) awarded to Prof. Stephen McDonald.


Publication Date



Kidney International Reports






16p. (p. 1477-1492)





Rights Statement

© 2022 International Society of Nephrology. Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license (

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