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In vitro inhibitory activities of sugarcane extract on avian Eimeria sporozoites

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posted on 2021-09-28, 00:12 authored by A Daneshmand, P Young, B Campbell, SK Kheravii, NK Sharma, R Afshari, DA Dias, Matthew FlavelMatthew Flavel, Barry KitchenBarry Kitchen, SB Wu
The current in vitro study aimed to investigate the effects of a processed sugarcane extract on the viability of avian Eimeria sporozoites. Treatments were applied to hatched sporozoites: 1) without additives (no-treatment control); 2) with ethanol; 3) with salinomycin; 4) with Polygain™. All treatments were incubated in RPMI media containing live sporozoites at 37 °C for 14 h and then the number of viable sporozoites were counted. Compared to the no-treatment control, Polygain™ decreased (P < 0.001) the counts of E. maxima, E. acervulina, E. bruneti, and E. mitis sporozoites to a level similar to salinomycin (P > 0.05). In conclusion, Polygain™ could be a potential candidate as an anticoccidial agent.

History

Publication Date

2021-12-01

Journal

International Journal for Parasitology: Drugs and Drug Resistance

Volume

17

Pagination

4p.

Publisher

Elsevier

ISSN

2211-3207

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The Author reserves all moral rights over the deposited text and must be credited if any re-use occurs. Documents deposited in OPAL are the Open Access versions of outputs published elsewhere. Changes resulting from the publishing process may therefore not be reflected in this document. The final published version may be obtained via the publisher’s DOI. Please note that additional copyright and access restrictions may apply to the published version.

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