This project was supported by a La Trobe University RFA Understanding Diseases Grant (M.K-L), and in part, by the La Trobe University Stone Fellowship (D. W. G), the Australian National Health and Medical Research Council (Project: M. K-L 1107800, D.W.G 1139489,1141964), and funding support from La Trobe University (M. K-L, D.W.G).