File(s) stored somewhere else
Please note: Linked content is NOT stored on La Trobe and we can't guarantee its availability, quality, security or accept any liability.
Efficacy of rehabilitation programs for improving muscle strength in people with hip or knee osteoarthritis: a systematic review with meta-analysis
journal contributionposted on 09.12.2020, 03:26 by Anita ZachariasAnita Zacharias, Rodney GreenRodney Green, Adam SemciwAdam Semciw, Michael KingsleyMichael Kingsley, Tania PizzariTania Pizzari
© 2014 Osteoarthritis Research Society International.
To analyse the effect of exercise-based rehabilitation programs for improving lower limb muscle strength in individuals with hip or knee osteoarthritis (OA). A systematic search utilizing seven databases identified randomized controlled trials (RCTs) evaluating lower limb strength outcomes of exercise-based interventions for participants with hip or knee OA. All studies were screened for eligibility and methodological quality. Quality of evidence was assessed using Grading of Recommendation, Assessment, Development and Evaluation (GRADE) approach. Data were pooled and meta-analyses performed where appropriate.Forty RCTs were included and the majority (77%) involved resistance based exercise programs. For knee OA populations, there was high quality evidence for improved knee extension (standardized mean difference (SMD)=0.47, 95% confidence intervals (CI) 0.29, 0.66) and flexion strength (SMD=0.74, 95% CI 0.56, 0.92) with low-intensity resistance program when compared to a control at short term (ST) follow-up. There was moderate quality evidence for a large effect favouring high-intensity resistance programs (SMD=0.76, 95% CI 0.47, 1.06) when compared to a control. This effect was sustained at intermediate term (IT) follow-up (SMD=0.80, 95% CI 0.44, 1.17). Few studies reported on outcomes at long term (LT) follow-up. Only one study reported on a population with hip OA. When compared to a control group, high-intensity resistance exercise demonstrated moderate quality of evidence for large and sustained improvements for knee muscle strength in knee OA patients. Further work is needed to compare different modes of exercise at a LT follow-up for knee OA patients and to address the dearth of literature evaluating exercise interventions in people with hip OA.
JournalOsteoarthritis and Cartilage
Pagination22p. (p. 1752-1773)
Rights StatementThe Author reserves all moral rights over the deposited text and must be credited if any re-use occurs. Documents deposited in OPAL are the Open Access versions of outputs published elsewhere. Changes resulting from the publishing process may therefore not be reflected in this document. The final published version may be obtained via the publisher’s DOI. Please note that additional copyright and access restrictions may apply to the published version.
Science & TechnologyLife Sciences & BiomedicineOrthopedicsRheumatologyOsteoarthritisHipKneeInterventionMuscle strengthExerciseRANDOMIZED CONTROLLED-TRIALOLDER-ADULTSEXERCISE PROGRAMPHYSIOTHERAPY MANAGEMENTFUNCTIONAL-CAPACITYISOKINETIC EXERCISEPHYSICAL-THERAPYCLINICAL-TRIALSPEDRO SCALEQUALITYHumansOsteoarthritis, KneeOsteoarthritis, HipRange of Motion, ArticularExercise TherapyProgram EvaluationMuscle StrengthArthritis & Rheumatology1106 Human Movement and Sports Sciences