La Trobe

Dendritic cells shape TCF1+CD8+ progenitor T cell heterogeneity

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posted on 2025-02-07, 05:30 authored by Sonia GhilasSonia Ghilas, Lisa MielkeLisa Mielke

In two elegant studies, Tyler Jacks’ group and colleagues unveil crucial interactions between dendritic cells and TCF1+CD8+ progenitor T cells, shaping their heterogeneity and offering potential to design new putative cancer immunotherapies and vaccines.

Funding

The authors were supported by Victorian Cancer Agency Fellowship MCRF18027 and National Health and Medical Research Council of Australia Ideas Grant APP1185513 awarded to L.A.M.

History

Publication Date

2021-12-01

Journal

Trends in Immunology

Volume

42

Issue

12

Pagination

1063-1065

Publisher

Cell Press/Elsevier

ISSN

1471-4906

Rights Statement

© 2021 Crown. Published by Elsevier Ltd. All rights reserved. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/

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    Categories

    Keywords

    Stem Cell ResearchVaccine RelatedImmunizationCancerCD8-Positive T-LymphocytesDendritic CellsHepatocyte Nuclear Factor 1-alphaImmunotherapy

    Licence

    CC BY-NC-ND 4.0

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