Dendritic cells shape TCF1+CD8+ progenitor T cell heterogeneity

Ghilas, Sonia; Mielke, Lisa

doi:10.1016/j.it.2021.10.013

Dendritic cells shape TCF1+CD8+ progenitor T cell heterogeneity

journal contribution

posted on 2025-02-07, 05:30 authored by Sonia Ghilas, Lisa MielkeLisa Mielke

In two elegant studies, Tyler Jacks’ group and colleagues unveil crucial interactions between dendritic cells and TCF1+CD8+ progenitor T cells, shaping their heterogeneity and offering potential to design new putative cancer immunotherapies and vaccines.

Funding

The authors were supported by Victorian Cancer Agency Fellowship MCRF18027 and National Health and Medical Research Council of Australia Ideas Grant APP1185513 awarded to L.A.M.

History

Publication Date

2021-12-01

Journal

Trends in Immunology

Volume

42

Issue

12

Pagination

1063-1065

Publisher

Cell Press/Elsevier

ISSN

1471-4906

Rights Statement

Publisher DOI

https://doi.org/10.1016/j.it.2021.10.013

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Keywords

Stem Cell Research Vaccine Related Immunization Cancer CD8-Positive T-Lymphocytes Dendritic Cells Hepatocyte Nuclear Factor 1-alpha Immunotherapy

Licence

CC BY-NC-ND 4.0

Dendritic cells shape TCF1+CD8+ progenitor T cell heterogeneity

Funding

The authors were supported by Victorian Cancer Agency Fellowship MCRF18027 and National Health and Medical Research Council of Australia Ideas Grant APP1185513 awarded to L.A.M.

History

Publication Date

Journal

Volume

Issue

Pagination

Publisher

ISSN

Rights Statement

Publisher DOI

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Keywords

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