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CircR2Cancer: a manually curated database of associations between circRNAs and cancers

journal contribution
posted on 15.12.2020, 07:18 by W Lan, M Zhu, Q Chen, B Chen, J Liu, M Li, Yi-Ping Phoebe Chen
© The Author(s) 2020. Published by Oxford University Press. Accumulating evidences have shown that the deregulation of circRNA has close association with many human cancers. However, these experimental verified circRNA-cancer associations are not collected in any database. Here, we develop a manually curated database (circR2Cancer) that provides experimentally supported associations between circRNAs and cancers. The current version of the circR2Cancer contains 1439 associations between 1135 circRNAs and 82 cancers by extracting data from existing literatures and databases. In addition, circR2Cancer contains the information of cancer exacted from Disease Ontology and basic biological information of circRNAs from circBase. At the same time, circR2Cancer provides a simple and friendly interface for users to conveniently browse, search and download the data. It will be a useful and valuable resource for researchers to understanding the regulation mechanism of circRNA in cancers. DATABASE URL: http://www.biobdlab.cn:8000.

History

Publication Date

11/11/2020

Journal

Database: the journal of biological databases and curation

Volume

2020

Article Number

baaa085

Pagination

8p. (p. 1-8)

Publisher

Oxford University Press

ISSN

1758-0463

Rights Statement

The Author reserves all moral rights over the deposited text and must be credited if any re-use occurs. Documents deposited in OPAL are the Open Access versions of outputs published elsewhere. Changes resulting from the publishing process may therefore not be reflected in this document. The final published version may be obtained via the publisher’s DOI. Please note that additional copyright and access restrictions may apply to the published version.

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