journal contribution
posted on 2024-01-10, 03:57 authored by A Ullah, Y Huang, Kening ZhaoKening Zhao, Y Hua, S Ullah, MU Rahman, J Wang, Q Wang, X Hu, L Zheng Extracellular vesicles (EVs) are a heterogeneous group of lipid membrane-enclosed compartments that contain different biomolecules and are released by almost all living cells, including fungal genera. Fungal EVs contain multiple bioactive components that perform various biological functions, such as stimulation of the host immune system, transport of virulence factors, induction of biofilm formation, and mediation of host–pathogen interactions. In this review, we summarize the current knowledge on EVs of human pathogenic fungi, mainly focusing on their biogenesis, composition, and biological effects. We also discuss the potential markers and therapeutic applications of fungal EVs.
Funding
The efforts in preparing this review were supported by grants from the National Science Fund for Distinguished Young Scholars (82025024) and National Natural Science Foundation of China (82102459 and 82272384), China Postdoctoral Science Foundation (2019M662990), the President Foundation of Nanfang Hospital Southern Medical University (2021B023), Guangdong Basic and Applied Basic Research Foundation (2021A1515110578), Guangzhou Science and Technology Plan Project-Basic and Applied Basic Research Projects (202201011480), Clinical research subject of Guangdong Medical Association (yueyihui2020[342]).
History
Publication Date
2023-08-19Journal
BMC MicrobiologyVolume
23Issue
1Article Number
227 (2023)Pagination
15p.Publisher
Springer NatureISSN
1471-2180Rights Statement
© The Author(s) 2023. Licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the licence, and indicate if changes were made. The images or other third party material in this article are included in the article's licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view the licence: http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
