C-H, Si-H and C-F abstraction with an extremely electron poor I(iii) reagent
journal contribution
posted on 2025-02-04, 04:59 authored by Tania TaniaTania Tania, Marcus SceneyMarcus Sceney, Jason BennettsJason Bennetts, Lachlan BarwiseLachlan Barwise, Keith WhiteKeith White, Jason DuttonJason Dutton<p dir="ltr">The recently discovered I(iii) reagent NO<sub>2</sub>-C<sub>6</sub>H<sub>4</sub>-I(OTf)<sub>2</sub> is found to rapidly react with hydride sources, including HSiEt<sub>3</sub> and relatively hydridic C-H precursors. These represent the first distinct reactions involving direct hydride abstraction by I(iii) under ambient conditions. Direct C-F abstraction is also demonstrated, as well as oxidation of cyclic alkenes to aromatic rings, all representing new reactions for I(iii) demonstrating the very high reactivity of NO<sub>2</sub>-C<sub>6</sub>H<sub>4</sub>-I(OTf)<sub>2.</sub></p>
