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Association between alcohol consumption and the risk of stroke in middle-aged and older adults in China

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posted on 2025-01-15, 00:37 authored by Yong Gan, J Feng, Y Zhu, L Li, X Shen, Y Lou, Robin RoomRobin Room, Z Lei, W Yue, Heng JiangHeng Jiang, Z Lu
Objective: This study aimed to investigate the association between alcohol consumption and the prevalence of stroke in Chinese adults aged 40 years and over. Method: We conducted a cross-sectional analysis among 113,573 Chinese adults aged ≥ 40 years in the China National Stroke Prevention Project (2014–2015) to examine correlations of alcohol consumption with the prevalence of stroke. Logistic regression models were used to calculate odds ratios (ORs) and 95% confidence intervals (CIs), controlling for various confounders, e.g., gender, age, smoking, physical activity and other health conditions. Results: Within the study population, a total of 12,753 stroke survivors were identified. The prevalence of light to moderate and of heavy alcohol consumption was 10.1% and 5.7% respectively. The multivariate logistic regression results show that light to moderate alcohol consumption was associated with reduced risk of stroke of all types [0.91 (95%CI: 0.85–0.97)] and of ischemic stroke [0.90 (0.84–0.97)]. No association was found between alcohol consumption and hemorrhagic stroke. Compared with abstainers, the adjusted ORs of all stroke were 0.83 (0.75–0.92) for those who drank 11–20 years, and no association was found between 1 and 10 years or over 20 years of drinking and risk of stroke. Conclusions: These results indicate that light to moderate alcohol consumption may be protective against all and ischemic stroke, and heavy drinking was not significantly associated with risk of all stroke in China. No association between alcohol consumption and hemorrhagic stroke was found.

Funding

This study was funded by the Ministry of Finance of the People's Republic of China, China (Finance and Social Security [2011] Document No. 61, Ministry of Finance); National Social Science Foundation of China, China (Grant No. 18ZDA085); China Postdoctoral Science Foundation, China (2018M630870); National Health and Medical Research Council, Australia (GNT1141325) and Australian Research Council - Discovery, Australia (DP200101781).

History

Publication Date

2021-12-01

Journal

Drug and Alcohol Dependence

Volume

229

Issue

Part B

Article Number

109134

Pagination

9p.

Publisher

Elsevier

ISSN

0376-8716

Rights Statement

© 2021 Elsevier. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/