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Anthocyanin intake and physical activity: Associations with the lipid profile of a US working population
journal contributionposted on 2020-12-02, 04:06 authored by MS Hershey, M Sotos-Prieto, M Ruiz-Canela, Miguel Martinez-Gonzalez, A Cassidy, S Moffatt, SN Kales
© 2020 by the authors. Licensee MDPI, Basel, Switzerland. While growing evidence exists on the independent associations between anthocyanins and physical activity on cardiovascular disease (CVD) risk determinants, the possible interaction between these exposures has not yet been studied. We aimed to study the potential synergism between anthocyanin intake and physical activity on lipid profile measures. This cross-sectional study was conducted among 249 US career firefighters participating in the Feeding America’s Bravest trial. Anthocyanin intake was calculated using a validated food frequency questionnaire (FFQ) and physical activity level by a validated questionnaire. Multivariable linear regression models determined the extent to which anthocyanin intake and physical activity predicted lipid parameters. Generalized linear models were used for joint effect and interaction analyses on the multiplicative and additive scales. Both anthocyanins and physical activity were independently inversely associated with total cholesterol:high density lipoprotein (HDL) cholesterol. Only physical activity was inversely associated with triglycerides, low density lipoprotein (LDL) cholesterol:HDL, and triglycerides (TG):HDL. Although the combined exposure of low anthocyanin intake and low physical activity was associated with lower (RR = 2.83; 95% CI: 1.42 to 5.67) HDL cholesterol <40 mg/dL, neither multiplicative (p = 0.72) nor additive interactions were detected (relative excess risk due to interaction (RERI): 0.02; 95% CI: −1.63 to 1.66; p = 0.98). Our findings provide insight on the potential synergism between anthocyanin intake and physical activity on the lipid profile.
The authors acknowledge the Advisory Board and the data advisory monitoring board (DAMB), Indianapolis Fire Department (IFD), Fishers Fire Department, Indianapolis Local 416 support, and the National Fire Organizations; International Association of Fire Fighters, National Volunteer Fire Council, National Fallen Firefighters' Foundation, The Fire Protection Research Foundation, and International Association of Fire Chiefs that support the research, as well as the firefighters and their families for their participation.
PublisherMultidisciplinary Digital Publishing Institute (MDPI)
Rights StatementThe Author reserves all moral rights over the deposited text and must be credited if any re-use occurs. Documents deposited in OPAL are the Open Access versions of outputs published elsewhere. Changes resulting from the publishing process may therefore not be reflected in this document. The final published version may be obtained via the publisher’s DOI. Please note that additional copyright and access restrictions may apply to the published version.
Science & TechnologyLife Sciences & BiomedicinePhysical SciencesBiochemistry & Molecular BiologyChemistry, MultidisciplinaryChemistryanthocyaninsphysical activitylipid profilecardiovascular diseaseworking populationCARDIOVASCULAR RISK-FACTORSTRIAL SEQUENTIAL-ANALYSISDISEASE PREVENTIONMEDITERRANEAN DIETHEALTHFUL DIETEXERCISEMETAANALYSISPROMOTEADULTSOrganic Chemistry