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A new approach to evidence synthesis in traumatic brain injury: Living systematic reviews.

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journal contribution
posted on 2022-05-05, 00:01 authored by Anneliese SynnotAnneliese Synnot, RL Gruen, D Menon, EW Steyerberg, A Buki, W Peul, JH Elliott, A Maas
Living systematic reviews (LSRs) are online summaries of health care research that are updated as new research becomes available. This new development in evidence synthesis is being trialled as part of the Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) project. We will develop and sustain an international TBI knowledge community that maintains up-to-date, high quality LSRs of the current state of knowledge in the most important questions in TBI. Automatic search updates will be run three-monthly, and newly identified studies incorporated into the review. Review teams will seek to publish journal updates at regular intervals, with abridged updates available more frequently online. Future project stages include the integration of LSR and other study findings into "living"clinical practice guidance. It is hoped these efforts will go some way to bridging current temporal disconnects between evidence, guidelines, and practice in TBI.


Publication Date



Journal of Neurotrauma






3p. (p. 1-3)


Mary Ann Liebert



Rights Statement

ª Anneliese Synnot et al. 2016; Published by Mary Ann Liebert, Inc. This Open Access article is distributed under the terms of the Creative Commons Attribution Noncommercial License ( which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.