A lipidomic based metabolic age score captures cardiometabolic risk independent of chronological age

This research was supported by the National Health and Medical Research Council of Australia (Project grant APP1101320) and Investigator grants to KH, JES, DJM, CG and PJM. This work was also supported in part by the Victorian Government’s Operational Infrastructure Support Program. The AusDiab study, initiated and coordinated by the International Diabetes Institute, and subsequently coordinated by the Baker Heart and Diabetes Institute, gratefully acknowledges the support and assistance given by the AusDiab Study Team and all the study participants. Also, for funding or logistical support, we are grateful to: National Health and Medical Research Council (NHMRC grant 233200), Australian Government Department of Health and Ageing. Abbott Australasia Pty Ltd, Alphapharm Pty Ltd, AstraZeneca, Bristol-Myers Squibb, City Health Centre-Diabetes Service-Canberra, Department of Health and Community Services - Northern Territory, Department of Health and Human Services – Tasmania, Department of Health – New South Wales, Department of Health – Western Australia, Department of Health – South Australia, Department of Human Services – Victoria, Diabetes Australia, Diabetes Australia Northern Territory, Eli Lilly Australia, Estate of the Late Edward Wilson, GlaxoSmithKline, Jack Brockhoff Foundation, Janssen-Cilag, Kidney Health Australia, Marian & FH Flack Trust, Menzies Research Institute, Merck Sharp & Dohme, Novartis Pharmaceuticals, Novo Nordisk Pharmaceuticals, Pfizer Pty Ltd, Pratt Foundation, Queensland Health, Roche Diagnostics Australia, Royal Prince Alfred Hospital, Sydney, Sanofi Aventis, sanofi-synthelabo, and the Victorian Government’s OIS Program. JES, DJM and PJM are supported by Investigator grants from the National Health and Medical Research Council of Australia. The authors wish to thank the staff at the Western Australian Data Linkage Branch and Death Registrations and Hospital Morbidity Data Collection for the provision of linked health data fo