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A contemporary understanding of iron metabolism in active premenopausal females

Version 2 2024-07-11, 06:02
Version 1 2022-08-15, 05:49
journal contribution
posted on 2024-07-11, 06:02 authored by Claire E Badenhorst, Adrienne ForsythAdrienne Forsyth, Andrew GovusAndrew Govus
Iron metabolism research in the past decade has identified menstrual blood loss as a key contributor to the prevalence of iron deficiency in premenopausal females. The reproductive hormones estrogen and progesterone influence iron regulation and contribute to variations in iron parameters throughout the menstrual cycle. Despite the high prevalence of iron deficiency in premenopausal females, scant research has investigated female-specific causes and treatments for iron deficiency. In this review, we provide a comprehensive discussion of factors that influence iron status in active premenopausal females, with a focus on the menstrual cycle. We also outline several practical guidelines for monitoring, diagnosing, and treating iron deficiency in premenopausal females. Finally, we highlight several areas for further research to enhance the understanding of iron metabolism in this at-risk population.

History

Publication Date

2022-07-28

Journal

Frontiers in Sports and Active Living

Volume

4

Pagination

27p.

Publisher

Frontiers Media SA

Rights Statement

© 2022 Badenhorst, Forsyth and Govus. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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