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Methamphetamine use and HIV risk behavior among men who inject drugs: causal inference using coarsened exact matching

journal contribution
posted on 12.11.2020, 20:30 by M Noroozi, Peter Higgs, A Noroozi, B Armoon, B Mousavi, R Alikhani, MR Bazrafshan, AN Astaneh, A Bayani, LF Moghaddam
© 2020 The Author(s). Background: Understanding the association between methamphetamine (MA) use and HIV risk behavior among people who inject drugs (PWID) will assist policy-makers and program managers to sharpen the focus of HIV prevention interventions. This study examines the relationship between MA use and HIV risk behavior among men who inject drugs (MWID) in Tehran, Iran, using coarsened exact matching (CEM). Methods: Data for these analyses were derived from a cross-sectional study conducted between June and July 2016. We assessed three outcomes of interest - all treated as binary variables, including distributive and receptive needle and syringe (NS) sharing and condomless sex during the month before interview. Our primary exposure of interest was whether study participants reported any MA use in the month prior to the interview. Firstly, we report the descriptive statistics for the pooled samples and matched sub-samples using CEM. The pooled and matched estimates of the associations and their 95% CI were estimated using a logistic regression model. Results: Overall, 500 MWID aged between 18 and 63 years (mean = 28.44, SD = 7.22) were recruited. Imbalances in the measured demographic characteristics and risk behaviors between MA users and non-users were attenuated using matching. In the matched samples, the regression models showed participants who reported MA use were 1.82 times more likely to report condomless sex (OR = 1.82 95% CI 1.51, 4.10; P = 0.031), and 1.35 times more likely to report distributive NS sharing in the past 30 days, as compared to MA non-users (OR = 1.35 95% CI 1.15-1.81). Finally, there was a statistically significant relationship between MA use and receptive NS sharing in the past month. People who use MA in the last month had higher odds of receptive NS sharing when compared to MA non-users (OR = 4.2 95% CI 2.7, 7.5; P = 0.013). Conclusions: Our results show a significant relationship between MA use and HIV risk behavior among MWID in Tehran, Iran. MA use was related with increased NS sharing, which is associated with higher risk for HIV exposure and transmission.

Funding

This Project was funded by the University of Social Welfare and Rehabilitation Sciences (USWRS), Tehran, Iran

History

School

  • School of Psychology and Public Health

Publication Date

21/09/2020

Journal

Harm Reduction Journal

Volume

17

Issue

1

Article Number

66

Pagination

7p. (p. 1-7)

Publisher

BioMed Central

ISSN

1477-7517

Rights Statement

The Author reserves all moral rights over the deposited text and must be credited if any re-use occurs. Documents deposited in OPAL are the Open Access versions of outputs published elsewhere. Changes resulting from the publishing process may therefore not be reflected in this document. The final published version may be obtained via the publisher’s DOI. Please note that additional copyright and access restrictions may apply to the published version.

Licence

Exports